Treatment guidelines recommend Aimovig as an option for preventing episodic or chronic migraine headaches in people who: can't take other medications because of side effects or drug interactions can't reduce their number of monthly migraine headaches enough with other medications Treatment guidelines recommend Topiramate as an option for preventing episodic migraine headaches.
Clinical studies have not directly compared the effectiveness of these two drugs in preventing migraine headaches. But the drugs have been studied separately. Episodic migraine Separate studies of Aimovig and Topamax showed trokendi xr aiuta con la perdita di peso both drugs were effective in preventing episodic migraine headaches: In Aimovig clinical studies, up to 50 percent of people with episodic migraine who received mg cut their migraine days by at least half over six months trokendi xr aiuta con la perdita di peso treatment.
About 40 percent of people who received 70 mg saw similar results. In clinical studies of people with episodic migraine who took Topamax, those aged 12 years and older had about two fewer migraine headaches each month. Children aged 12 through 17 with episodic migraine had three fewer migraine headaches each month.
Chronic migraine Separate studies of the drugs showed that both Aimovig and Topamax were effective in preventing chronic migraine headaches: In a three-month clinical study of Aimovig, about 40 percent of people with chronic migraine headaches who received either 70 mg or mg had half as many migraine days or fewer after treatment.
In a study that looked at the results of several clinical trials found that in people with chronic migraine, Topamax reduced the number of migraine headaches or headaches by about five to nine each month.
Costs Aimovig and Topamax are both brand-name medications. Brand-name medications usually cost more than generic medications.
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Aimovig is not available in a generic form, but Topamax comes as a generic called topiramate. According to estimates from GoodRx. And topiramate, the generic form of Topamax, will cost less than either Topamax or Aimovig.
The actual price you would pay for any of these drugs would depend on your dose, your insurance plan, your location, and the pharmacy you use.
Che cos'è Aimovig?
Aimovig and alcohol There is no interaction between Aimovig and alcohol. Still, some people may feel the drug is less effective if they drink alcohol while taking Aimovig. This is because alcohol can be a migraine trigger for many people. Even small amounts of alcohol can cause a migraine for them. You should avoid drinks that contain alcohol if you find that alcohol causes more painful or more frequent migraine headaches.
Aimovig interactions Many drugs can interact with other medications. Different effects can be caused by different interactions. For example, some interactions can interfere with how well a drug works, while others can cause more side effects. Aimovig doesn't generally have drug interactions.
This is because of the way Aimovig is processed in your body. How Aimovig is metabolized Many drugs, herbs, and supplements are metabolized processed by enzymes in your liver. But monoclonal antibody drugs, such as Aimovig, are not usually processed in the liver.
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Instead, this kind of drug is processed inside other cells in your body. Because Aimovig isn't processed in the liver like many other drugs are, it generally doesn't interact with other drugs. If you have any concerns about combining Aimovig with other medications you may be taking, talk with your doctor.
And be sure to tell them about all prescription, over-the-counter, and other medications you take. You should also tell them about any herbs, vitamins, and nutritional supplements you use. Instructions on how to take Aimovig Aimovig comes as an injection that's given under your skin subcutaneous. You give yourself the injection at home once per month. The first time you get a prescription controindicazioni del bruciagrassi Aimovig, your healthcare provider will explain how to give yourself the injection.
Aimovig comes in a single-dose 70 mg autoinjector. Each autoinjector contains only one dose and is meant to be used once and then thrown away. If your doctor prescribes mg per month, you'll use two autoinjectors each month. Below is information on how to use the prefilled syringe. For other details, video, and images of injection instructions, see the manufacturer's website.
How to inject Your doctor will prescribe either 70 mg once per trokendi xr aiuta con la perdita di peso or mg once per month. If you're prescribed 70 mg monthly, you'll give yourself one injection.
Intro to Topiramate / Topamax
If you're prescribed mg monthly, you'll give yourself two separate injections, one after the other. Preparing to inject Take your Aimovig autoinjector from the refrigerator 30 minutes before you plan to do your injection. This will allow the drug to warm up to room temperature. Leave the cap on the autoinjector device until you're ready to inject the drug. Do not try to warm up the autoinjector faster by microwaving it or running hot water over it. Also, do not shake the autoinjector.
Doing these things can make Aimovig less safe and effective. If you accidentally drop the autoinjector, do not use it. Small components of the autoinjector may be broken inside, even if you cannot see any damage. While you're waiting for Aimovig to come to room temperature, find other supplies you will need. Questi includono: an alcohol wipe adhesive bandages disposal container for sharps Check the autoinjector and make sure the medication does not look cloudy.
It should be colorless to very pale yellow in color.
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If it looks discolored, cloudy, or has any solid pieces in the liquid, do not use it. If needed, contact your doctor about getting a new one. Also, check the expiration date on the device to make sure the drug is not expired. After washing your hands with soap and water, choose an injection site. Aimovig can be injected at these places: your belly at least 2 inches away from your belly button the front of your thighs at least 2 inches above your knee or 2 inches below your groin the back of your upper arms if someone else is giving you the injection Use an alcohol wipe to clean the area you plan to inject.
Let the alcohol dry completely before you inject the medication. Do not inject Aimovig into an area of skin that's bruised, hard, red, or tender. Using the autoinjector Pull the white cap straight off the autoinjector. Do this no more than five minutes before you will use the device. Stretch or pinch the area of skin where you plan to inject the drug.
Create a firm area of skin about 2 inches wide for your injection. Place the autoinjector on your skin at a degree angle. Firmly press down onto your skin as far as it will go. Press the purple start button at the top of the autoinjector until you hear a click. Release the purple start button but continue holding the autoinjector down onto your skin until the window on the autoinjector turns yellow.
You may also hear or feel a "click. It's important to do this step to make sure you get the entire dose. Remove the autoinjector from your skin and dispose of it in your sharps disposal container. If there is any blood at the injection site, press a cotton ball or gauze onto the skin, but do not rub.
Use an adhesive bandage if needed. If your dose is mg per month, repeat these steps with the second autoinjector. Do not use the same injection site as the first injection.
Timing Aimovig should be taken once per month. It can be taken at any time of the day. If you miss a dose, take Aimovig as soon as you remember. The next dose should be one month after you take that one. Using a medication reminder tool can help you remember to take Aimovig on schedule. Taking Aimovig with food Aimovig can be taken with or without food. Conservazione Aimovig should be stored in the refrigerator. It can be taken out of the refrigerator but must be used within seven days.
Do not put it back in the refrigerator once it has been taken out and brought to room temperature. Don't freeze Aimovig. Also, keep it in its original package to protect it from light. How Aimovig works Aimovig is a drug called a monoclonal antibody. This kind of drug is made in a lab from immune system proteins. Aimovig works by stopping the activity of a protein in your body called calcitonin gene-related peptide CGRP.
CGRP can cause inflammation and vasodilation widening of blood vessels in your brain. The inflammation and vasodilation brought on by CGRP is a possible cause of migraine headaches. In fact, when a migraine headache is starting to occur, people have higher levels of CGRP in their bloodstream.
Aimovig helps prevent a migraine by stopping the activity of CGRP. While most medications work by affecting many substances in your body, lotta contro la perdita di peso antibodies such as Aimovig work on only one protein in the body.
Because of this, Aimovig may cause fewer drug interactions and side effects. This can make it a good treatment option for people who can't take other medications due to side effects or interactions. Aimovig may also be a good treatment option for people who haven't found another medication that can reduce their migraine days enough. How long does it take to work? After you start taking Aimovig, it may take a few weeks to see an improvement in your migraine headaches.
Aimovig may take full effect after several months. Many people who took Aimovig during clinical trials had fewer migraine days within one month of starting the drug.
People also had fewer migraine days after continuing the treatment over several months. Aimovig and pregnancy There haven't been enough studies done to know if Aimovig is safe to take during pregnancy.
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Animal studies did not show any risk to the pregnancy when Aimovig was given to a pregnant female. However, animal studies don't always predict whether drugs will be safe in humans. If you're pregnant or considering becoming pregnant, talk with your doctor to see if Aimovig is right for you. You may need to wait until you're no longer pregnant to use Aimovig. Aimovig and breastfeeding It's not known if Aimovig passes into breast milk. Therefore, it's not clear if Aimovig is safe to use while breastfeeding.
If you're considering treatment with Aimovig while you're breastfeeding your child, talk with your doctor about the benefits and risks.
You may need to stop breastfeeding if you begin taking Aimovig. Common questions about Aimovig Here are answers to some frequently asked questions about Aimovig. Does stopping Aimovig cause withdrawal?
There have been no reports of withdrawal effects after stopping Aimovig. However, Aimovig was only recently approved by the FDA, in The number of people who have used and stopped Aimovig therapy is still limited. Is Aimovig a biologic? Aimovig is a monoclonal antibody, which is a type of biologic. A biologic is a drug that's developed from biological material, rather than chemicals. Because they interact with very specific immune system cells and proteins, biologics such as Aimovig are thought to have fewer side effects compared to drugs that affect a wider range of body systems, as other migraine drugs banner perdita di peso. Can you use Aimovig to treat a migraine?
Aimovig is only used to prevent a migraine headache before it starts. It will not work to treat a migraine that has already started.
Does Aimovig cure migraine? No, Aimovig will not cure migraine.
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Perdere peso per concepire medications are currently available to cure migraine. How is Aimovig different from other migraine drugs? Aimovig is different from most other migraine drugs because it was the first FDA-approved medication specifically made to prevent migraine headaches. Aimovig is part of a new class of drugs called calcitonin gene-related peptide CGRP antagonists.
Most other drugs used to prevent migraine headaches were actually developed for other reasons, such as treating seizures, high blood pressure, or depression. Many of these drugs are used off-label to prevent migraine headaches.